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Thyroid tumours in rats and hepatomas in mice after griseofulvin treatment.

Griseofulvin, an antibiotic used to treat dermatophystosis, was tested for carcinogenicity in mice, rats and hamsters. Three groups of mice and rats were given the drug in powdered diet in alternating 5-week periods for life, at dose levels of 3.0%, 1.5% and 0.3% (mice) and 2.0%, 1.0% and 0.2% (rats...

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Detalhes bibliográficos
Main Authors: Rustia, M., Shubik, P.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1978
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2009728/
https://ncbi.nlm.nih.gov/pubmed/698038
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