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Thyroid tumours in rats and hepatomas in mice after griseofulvin treatment.

Griseofulvin, an antibiotic used to treat dermatophystosis, was tested for carcinogenicity in mice, rats and hamsters. Three groups of mice and rats were given the drug in powdered diet in alternating 5-week periods for life, at dose levels of 3.0%, 1.5% and 0.3% (mice) and 2.0%, 1.0% and 0.2% (rats...

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Библиографические подробности
Главные авторы: Rustia, M., Shubik, P.
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 1978
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2009728/
https://ncbi.nlm.nih.gov/pubmed/698038
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