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Squamous Lesions in the Lungs of Rats Exposed to Tobacco-smoke-condensate Fractions by Repeated Intratracheal Instillation

Twice-weekly intratracheal instillations in rats of up to 24 mg of Fraction (R + P)G suspended in either infusine (I) or buffered saline/gelatine (BS/G) gave rise to foci of squamous metaplasia of alveolar epithelium (SqM) and squamous neoplasms (SqN). Fraction (R + P)G, which is a fraction of cigar...

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Detalhes bibliográficos
Main Authors: Simons, P. J., Lee, P. N., Roe, F. J. C.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1978
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2009662/
https://ncbi.nlm.nih.gov/pubmed/678436
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