Response of rat lung to tobacco smoke condensate or fractions derived from it administered repeatedly by intratracheal instillation.

The repeated intratracheal instillation of cigarette smoke condensate (SWS) in rats at close to maximum tolerated dose levels failed to induce squamous neoplasms in the lungs although such treatment was associated with an increased incidence of cuboidal/columnar metaplasia (CCM) and squamous metapla...

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Main Authors: Davis, B. R., Whitehead, J. K., Gill, M. E., Lee, P. M., Butterworth, A. D., Roe, F. J.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1975
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2009461/
https://ncbi.nlm.nih.gov/pubmed/1156526
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