Kinetics of changes in the crypts of the jejunal mucosa of dimethylhydrazine-treated rats.

When symmetrical 1,2 dimethylhydrazine was administered to rats by weekly s.c. injection, 37% of the animals had developed small intestinal carcinomas after 21-27 weeks. These lesions were largely localized to duodenum and upper jejunum. At the same time there was a diffuse crypt hyperplasia in the...

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Bibliografske podrobnosti
Main Authors: Sunter, J. P., Appleton, D. R., Wright, N. A., Watson, A. J.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 1978
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2009617/
https://ncbi.nlm.nih.gov/pubmed/656298
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