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Kinetics of the non-neoplastic mucosa of the large bowel of dimethylhydrazine-treated rats.

Administration of 1,2 dimethylhydrazine (DMH) to rats by weekly s.c. injections causes the development of multiple epithelial tumours of the large bowel. These appear to arise as localized dysplastic abnormalities in hitherto apparently morphologically normal crypts. This study was undertaken in ord...

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Detalhes bibliográficos
Main Authors: Sunter, J. P., Watson, A. J., Appleton, D. R.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1981
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2010667/
https://ncbi.nlm.nih.gov/pubmed/7259959
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