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cDNA cloning and expression of bovine procollagen I N-proteinase: A new member of the superfamily of zinc-metalloproteinases with binding sites for cells and other matrix components

Procollagen N-proteinase (EC 3.4.24.14) cleaves the amino-propeptides in the processing of type I and type II procollagens to collagens. Deficiencies of the enzyme cause dermatosparaxis in cattle and sheep, and they cause type VIIC Ehlers–Danlos syndrome in humans, heritable disorders characterized...

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Autores principales: Colige, Alain, Li, Shi-Wu, Sieron, Aleksander L., Nusgens, Betty V., Prockop, Darwin J., Lapière, Charles M.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1997
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC20095/
https://ncbi.nlm.nih.gov/pubmed/9122202
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