In vivo N-Terminomics Highlights Novel Functions of ADAMTS2 and ADAMTS14 in Skin Collagen Matrix Building

A disintegrin and metalloproteinase with thrombospondin type I motif (ADAMTS)2 and ADAMTS14 were originally known for their ability to cleave the aminopropeptides of fibrillar collagens. Previous work using N-terminomic approach (N-TAILS) in vitro led to the identification of new substrates, includi...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Cédric Leduc, Laura Dupont, Loïc Joannes, Christine Monseur, Dominique Baiwir, Gabriel Mazzucchelli, Christophe Deroanne, Alain Colige, Mourad Bekhouche
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2021-03-01
Schriftenreihe:	Frontiers in Molecular Biosciences
Schlagworte:	ADAMTS collagen Ehlers-Danlos Syndrome (EDS) degradomics TAILS N-Terminomics
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fmolb.2021.643178/full
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!