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Identification of the second cluster of ligand-binding repeats in megalin as a site for receptor–ligand interactions

Megalin is a large cell surface receptor that mediates the binding and internalization of a number of structurally and functionally distinct ligands from the lipoprotein and protease:protease inhibitor families. To begin to address how megalin is able to bind ligands with unique structurally propert...

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Autors principals: Orlando, Robert A., Exner, Markus, Czekay, Ralf-Peter, Yamazaki, Hajime, Saito, Akihiko, Ullrich, Robert, Kerjaschki, Dontscho, Farquhar, Marilyn Gist
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences of the USA 1997
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC20094/
https://ncbi.nlm.nih.gov/pubmed/9122201
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