Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine

Lignende værker

• Enhanced oral bioavailability of paclitaxel in mice treated with the P-glycoprotein blocker SDZ PSC 833.
  af: van Asperen, J., et al.
  Udgivet: (1997)
• Substantial excretion of digoxin via the intestinal mucosa and prevention of long-term digoxin accumulation in the brain by the mdr 1a P-glycoprotein.
  af: Mayer, U., et al.
  Udgivet: (1996)
• Paclitaxel in self-micro emulsifying formulations: oral bioavailability study in mice
  af: Oostendorp, Roos L., et al.
  Udgivet: (2010)
• Increased accumulation of doxorubicin and doxorubicinol in cardiac tissue of mice lacking mdr1a P-glycoprotein
  af: Asperen, J van, et al.
  Udgivet: (1999)
• Cremophor EL causes (pseudo-) non-linear pharmacokinetics of paclitaxel in patients
  af: Tellingen, O van, et al.
  Udgivet: (1999)