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Inhibition of interleukin 1β converting enzyme family proteases reduces ischemic and excitotoxic neuronal damage

The interleukin 1β converting enzyme (ICE) family plays a pivotal role in programmed cell death and has been implicated in stroke and neurodegenerative diseases. During reperfusion after filamentous middle cerebral artery occlusion, ICE-like cleavage products and tissue immunoreactive interleukin 1β...

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Main Authors: Hara, Hideaki, Friedlander, Robert M., Gagliardini, Valeria, Ayata, Cenk, Fink, Klaus, Huang, Zhihong, Shimizu-Sasamata, Masao, Yuan, Junying, Moskowitz, Michael A.
格式: Artigo
語言:Inglês
出版: The National Academy of Sciences of the USA 1997
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC20033/
https://ncbi.nlm.nih.gov/pubmed/9050895
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