Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Gene Is a Risk Factor of Large-Vessel Atherosclerosis Stroke

BACKGROUND/PURPOSE: Genetic variation in proprotein convertase subtilisin/kexin type 9 (PCSK9) gene has been recently identified as an important determinant of plasma LDL-cholesterol and severity of coronary heart disease. We studied whether the PCSK9 gene is linked to the risk of ischemic stroke (I...

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Detalhes bibliográficos
Main Authors: Abboud, Shérine, Karhunen, Pekka J., Lütjohann, Dieter, Goebeler, Sirkka, Luoto, Teemu, Friedrichs, Silvia, Lehtimaki, Terho, Pandolfo, Massimo, Laaksonen, Reijo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2002510/
https://ncbi.nlm.nih.gov/pubmed/17940607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001043
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