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Vanadate supplements and 1,2-dimethylhydrazine induced colon cancer in mice: increased thymidine incorporation without enhanced carcinogenesis.

Because vanadate ion is a potent mitogen and accumulates in the gut of rodents fed vanadate supplements, effects of ammonium metavanadate in drinking water (10 ppm or 20 ppm) were studied on the development of large bowel neoplasms in mice treated with 1,2-dimethylhydrazine (DMH) (20 mg kg-1 weekly...

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Bibliografiske detaljer
Main Authors: Kingsnorth, A. N., LaMuraglia, G. M., Ross, J. S., Malt, R. A.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1986
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2001371/
https://ncbi.nlm.nih.gov/pubmed/2424483
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