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Vanadate supplements and 1,2-dimethylhydrazine induced colon cancer in mice: increased thymidine incorporation without enhanced carcinogenesis.

Because vanadate ion is a potent mitogen and accumulates in the gut of rodents fed vanadate supplements, effects of ammonium metavanadate in drinking water (10 ppm or 20 ppm) were studied on the development of large bowel neoplasms in mice treated with 1,2-dimethylhydrazine (DMH) (20 mg kg-1 weekly...

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Detalhes bibliográficos
Main Authors: Kingsnorth, A. N., LaMuraglia, G. M., Ross, J. S., Malt, R. A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1986
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2001371/
https://ncbi.nlm.nih.gov/pubmed/2424483
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