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Ancient Exaptation of a CORE-SINE Retroposon into a Highly Conserved Mammalian Neuronal Enhancer of the Proopiomelanocortin Gene

The proopiomelanocortin gene (POMC) is expressed in the pituitary gland and the ventral hypothalamus of all jawed vertebrates, producing several bioactive peptides that function as peripheral hormones or central neuropeptides, respectively. We have recently determined that mouse and human POMC expre...

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Hlavní autoři: Santangelo, Andrea M, de Souza, Flávio S. J, Franchini, Lucía F, Bumaschny, Viviana F, Low, Malcolm J, Rubinstein, Marcelo
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2000970/
https://ncbi.nlm.nih.gov/pubmed/17922573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.0030166
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