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Enhancer turnover and conserved regulatory function in vertebrate evolution

Mutations in regulatory regions including enhancers are an important source of variation and innovation during evolution. Enhancers can evolve by changes in the sequence, arrangement and repertoire of transcription factor binding sites, but whole enhancers can also be lost or gained in certain linea...

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Hlavní autoři: Domené, Sabina, Bumaschny, Viviana F., de Souza, Flávio S. J., Franchini, Lucía F., Nasif, Sofía, Low, Malcolm J., Rubinstein, Marcelo
Médium: Artigo
Jazyk:Inglês
Vydáno: The Royal Society 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3826500/
https://ncbi.nlm.nih.gov/pubmed/24218639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2013.0027
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