Genomic assessments of the frequent LOH region on 8p22-p21.3 in head and neck squamous cell carcinoma

Most human cancers are characterized by genetic instabilities. Chromosomal aberrations include segments of allelic imbalance identifiable by loss of heterozygosity (LOH) at polymorphic loci, which may be used to implicate regions harboring tumor suppressor genes. Here we performed whole genome LOH p...

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Hlavní autoři: Ye, Hui, Pungpravat, Nisa, Huang, Bau-Lin, Muzio, Lorenzo L., Mariggiò, Maria A., Chen, Zugen, Wong, David T., Zhou, Xiaofeng
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2000851/
https://ncbi.nlm.nih.gov/pubmed/17656251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cancergencyto.2007.04.003
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