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Genomic assessments of the frequent LOH region on 8p22-p21.3 in head and neck squamous cell carcinoma

Most human cancers are characterized by genetic instabilities. Chromosomal aberrations include segments of allelic imbalance identifiable by loss of heterozygosity (LOH) at polymorphic loci, which may be used to implicate regions harboring tumor suppressor genes. Here we performed whole genome LOH p...

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Main Authors: Ye, Hui, Pungpravat, Nisa, Huang, Bau-Lin, Muzio, Lorenzo L., Mariggiò, Maria A., Chen, Zugen, Wong, David T., Zhou, Xiaofeng
格式: Artigo
語言:Inglês
出版: 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2000851/
https://ncbi.nlm.nih.gov/pubmed/17656251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cancergencyto.2007.04.003
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