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Duloxetine pharmacokinetics are similar in Japanese and Caucasian subjects

WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT: The pharmacokinetics of duloxetine have been assessed in a number of clinical studies. Duloxetine is eliminated through oxidative metabolism via CYP1A2 and, to a lesser degree, CYP2D6. There is strong evidence that the prevalence of CYP2D6 phenotypes and the...

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Hlavní autoři: Chan, Clark, Yeo, Kwee P, Pan, Alan X, Lim, Maggie, Knadler, Mary P, Small, David S
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2000724/
https://ncbi.nlm.nih.gov/pubmed/17380590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2006.02770.x
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