Linkage between ‘disruption of inactivation’ and ‘reduction of K(+) selectivity’ among hERG mutants in the S5-P linker region

Antzeko izenburuak

• Gating Charges in the Activation and Inactivation Processes of the hERG Channel
  nork: Zhang, Mei, et al.
  Argitaratua: (2004)
• Dynamic conformational changes of extracellular S5–P linkers in the hERG channel
  nork: Jiang, Min, et al.
  Argitaratua: (2005)
• Effect of S5P α-helix charge mutants on inactivation of hERG K(+) channels
  nork: Clarke, C E, et al.
  Argitaratua: (2006)
• Transfer of Rolf S3-S4 Linker to hERG Eliminates Activation Gating but Spares Inactivation
  nork: Choveau, Frank S., et al.
  Argitaratua: (2009)
• A Molecular Switch Driving Inactivation in the Cardiac K(+) Channel hERG
  nork: Köpfer, David A., et al.
  Argitaratua: (2012)