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Effect of renal impairment on the pharmacokinetics of exenatide

What is already known about this subject Nonclinical studies have shown that exenatide is primarily cleared by the renal system. It was not known to what degree the clinical pharmacokinetics and tolerability would be affected by increasing renal impairment (RI). What this study adds: Patients with m...

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Autors principals: Linnebjerg, Helle, Kothare, Prajakti A, Park, Soomin, Mace, Kenneth, Reddy, Shobha, Mitchell, Malcolm, Lins, Robert
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2000650/
https://ncbi.nlm.nih.gov/pubmed/17425627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2007.02890.x
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