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Regulatory T cells enhance persistence of the zoonotic pathogen Seoul virus in its reservoir host

Hantaviruses are zoonotic pathogens that maintain a persistent infection in their reservoir hosts, yet the mechanisms mediating persistence remain unknown. Regulatory T cell responses cause persistent infection by suppressing proinflammatory and effector T cell activity; hantaviruses may exploit the...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Easterbrook, Judith D., Zink, M. Christine, Klein, Sabra L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2000529/
https://ncbi.nlm.nih.gov/pubmed/17878294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707453104
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