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Crystallographic trapping in the rebeccamycin biosynthetic enzyme RebC
The biosynthesis of rebeccamycin, an antitumor compound, involves the remarkable eight-electron oxidation of chlorinated chromopyrrolic acid. Although one rebeccamycin biosynthetic enzyme is capable of generating low levels of the eight-electron oxidation product on its own, a second protein, RebC,...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2007
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2000502/ https://ncbi.nlm.nih.gov/pubmed/17873060 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707190104 |
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