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Procollagen Triple Helix Assembly: An Unconventional Chaperone-Assisted Folding Paradigm

Fibers composed of type I collagen triple helices form the organic scaffold of bone and many other tissues, yet the energetically preferred conformation of type I collagen at body temperature is a random coil. In fibers, the triple helix is stabilized by neighbors, but how does it fold? The observat...

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Hlavní autoři: Makareeva, Elena, Leikin, Sergey
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2000351/
https://ncbi.nlm.nih.gov/pubmed/17925877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001029
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