The requirement for Phr1 in CNS axon tract formation reveals the corticostriatal boundary as a choice point for cortical axons

Phr1 is the single well-conserved murine ortholog of the invertebrate ubiquitin ligase genes highwire (in Drosophila) and rpm-1 (in Caenorhabditis elegans). The function and mechanism of action of highwire and rpm-1 are similar—both cell-autonomously regulate synaptogenesis by down-regulating the or...

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Bibliographic Details
Main Authors: Bloom, A. Joseph, Miller, Bradley R., Sanes, Joshua R., DiAntonio, Aaron
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2007
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2000324/
https://ncbi.nlm.nih.gov/pubmed/17901218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1592107
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