Target-specific requirements for enhancers of decapping in miRNA-mediated gene silencing

microRNAs (miRNAs) silence gene expression by suppressing protein production and/or by promoting mRNA decay. To elucidate how silencing is accomplished, we screened an RNA interference library for suppressors of miRNA-mediated regulation in Drosophila melanogaster cells. In addition to proteins know...

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Autors principals: Eulalio, Ana, Rehwinkel, Jan, Stricker, Mona, Huntzinger, Eric, Yang, Schu-Fee, Doerks, Tobias, Dorner, Silke, Bork, Peer, Boutros, Michael, Izaurralde, Elisa
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2007
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Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2000321/
https://ncbi.nlm.nih.gov/pubmed/17901217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.443107
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