Serrated pathway colorectal cancer in the population: genetic consideration

A significant proportion of colorectal cancer (CRC) develops through the serrated neoplasia pathway. Such tumours show a distinctive molecular phenotype of somatic BRAF mutations and widespread concordant methylation events in CpG islands (CIMP). These features are also observed in the polyps develo...

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Detalhes bibliográficos
Main Authors: Young, Joanne, Jenkins, Mark, Parry, Susan, Young, Bruce, Nancarrow, Derek, English, Dallas, Giles, Graham, Jass, Jeremy
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2007
Assuntos:
Serrated Colorectal Cancers in the Population
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2000271/
https://ncbi.nlm.nih.gov/pubmed/17566021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2007.126870
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