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Serrated pathway colorectal cancer in the population: genetic consideration
A significant proportion of colorectal cancer (CRC) develops through the serrated neoplasia pathway. Such tumours show a distinctive molecular phenotype of somatic BRAF mutations and widespread concordant methylation events in CpG islands (CIMP). These features are also observed in the polyps develo...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BMJ Group
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2000271/ https://ncbi.nlm.nih.gov/pubmed/17566021 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2007.126870 |
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