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The power of comparative and developmental studies for mouse models of Down syndrome

Since the genetic basis for Down syndrome (DS) was described, understanding the causative relationship between genes at dosage imbalance and phenotypes associated with DS has been a principal goal of researchers studying trisomy 21 (Ts21). Though inferences to the gene-phenotype relationship in huma...

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Autori principali: Moore, Clara S., Roper, Randall J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer New York 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1998891/
https://ncbi.nlm.nih.gov/pubmed/17653795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00335-007-9030-8
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