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Down syndrome mouse models have an abnormal enteric nervous system
Children with trisomy 21 (Down syndrome [DS]) have a 130-fold increased incidence of Hirschsprung disease (HSCR), a developmental defect in which the enteric nervous system (ENS) is missing from the distal bowel (i.e., distal bowel is aganglionic). Treatment for HSCR is surgical resection of agangli...
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| Vydáno v: | JCI Insight |
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| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Clinical Investigation
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6629165/ https://ncbi.nlm.nih.gov/pubmed/30998504 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.124510 |
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