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Down syndrome mouse models have an abnormal enteric nervous system
Children with trisomy 21 (Down syndrome [DS]) have a 130-fold increased incidence of Hirschsprung disease (HSCR), a developmental defect in which the enteric nervous system (ENS) is missing from the distal bowel (i.e., distal bowel is aganglionic). Treatment for HSCR is surgical resection of agangli...
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| Yayımlandı: | JCI Insight |
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| Asıl Yazarlar: | , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Clinical Investigation
2019
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6629165/ https://ncbi.nlm.nih.gov/pubmed/30998504 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.124510 |
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