Comparative genomics reveals functional transcriptional control sequences in the Prop1 gene

Mutations in PROP1 are a common genetic cause of multiple pituitary hormone deficiency (MPHD). We used a comparative genomics approach to predict the transcriptional regulatory domains of Prop1 and tested them in cell culture and mice. A BAC transgene containing Prop1 completely rescues the Prop1 mu...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Ward, Robert D., Davis, Shannon W., Cho, MinChul, Esposito, Constance, Lyons, Robert H., Cheng, Jan-Fang, Rubin, Edward M., Rhodes, Simon J., Raetzman, Lori T., Smith, Timothy P. L., Camper, Sally A.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer New York 2007
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1998882/
https://ncbi.nlm.nih.gov/pubmed/17557180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00335-007-9008-6
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados