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Development of “substrate-trapping” mutants to identify physiological substrates of protein tyrosine phosphatases

The identification of substrates of protein tyrosine phosphatases (PTPs) is an essential step toward a complete understanding of the physiological function of members of this enzyme family. PTPs are defined by a conserved catalytic domain harboring 27 invariant residues. From a mutagenesis study of...

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Bibliografiset tiedot
Päätekijät: Flint, Andrew J., Tiganis, Tony, Barford, David, Tonks, Nicholas K.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The National Academy of Sciences of the USA 1997
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC19976/
https://ncbi.nlm.nih.gov/pubmed/9050838
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