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The C-type lectin receptors CLEC-2 and Dectin-1, but not DC-SIGN, signal via a novel YXXL-dependent signalling cascade
The two lectin receptors, CLEC-2 and Dectin-1 have been shown to signal through a Syk-dependent pathway, despite the presence of only a single YXXL in their cytosolic tails. In the present study, we show that stimulation of CLEC-2 in platelets and in two mutant cell lines is dependent on the YXXL mo...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1997429/ https://ncbi.nlm.nih.gov/pubmed/17339324 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M609558200 |
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