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Asymmetrical β-actin mRNA translation in growth cones mediates attractive turning to netrin-1

Local protein synthesis regulates the turning of growth cones to guidance cues yet little is known about which proteins are synthesized or how they contribute to directional steering. Here we show that β-actin mRNA resides in Xenopus retinal growth cones where it binds to the RNA-binding protein, Vg...

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Detalhes bibliográficos
Main Authors: Leung, Kin-Mei, van Horck, Francisca PG, Lin, Andrew C, Allison, Rachel, Standart, Nancy, Holt, Christine E
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1997306/
https://ncbi.nlm.nih.gov/pubmed/16980963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn1775
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