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Conformational Flexibility in the Multidrug Efflux System Protein AcrA

Intrinsic resistance to multiple drugs in many gramnegative bacterial pathogens is conferred by resistance nodulation cell division efflux pumps, which are composed of three essential components as typified by the extensively characterized Escherichia coli AcrA-AcrB-TolC system. The inner membrane d...

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Detalhes bibliográficos
Main Authors: Mikolosko, Jonathan, Bobyk, Kostyantyn, Zgurskaya, Helen I., Ghosh, Partho
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1997295/
https://ncbi.nlm.nih.gov/pubmed/16531241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2005.11.015
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