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Conformational Flexibility in the Multidrug Efflux System Protein AcrA

Intrinsic resistance to multiple drugs in many gramnegative bacterial pathogens is conferred by resistance nodulation cell division efflux pumps, which are composed of three essential components as typified by the extensively characterized Escherichia coli AcrA-AcrB-TolC system. The inner membrane d...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mikolosko, Jonathan, Bobyk, Kostyantyn, Zgurskaya, Helen I., Ghosh, Partho
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1997295/
https://ncbi.nlm.nih.gov/pubmed/16531241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2005.11.015
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