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Integrin α(4)β(1) Regulates Migration across Basement Membranes by Lung Fibroblasts: A Role for Phosphatase and Tensin Homologue Deleted on Chromosome 10
Idiopathic pulmonary fibrosis is a disease that is characterized by fibroblast accumulation and activation in the distal airspaces of the lung. We hypothesized that fibrotic lung fibroblasts migrate/invade across basement membranes by integrin-mediated mechanisms as a means of entering alveoli. We d...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2003
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1997294/ https://ncbi.nlm.nih.gov/pubmed/12791582 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200301-041OC |
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