Neutrophil-epithelial crosstalk at the intestinal lumenal surface mediated by reciprocal secretion of adenosine and IL-6

Adenosine is formed in the intestinal lumen during active inflammation from neutrophil-derived 5′ AMP. Using intestinal epithelial cell line T84, we studied the effect of adenosine on the secretion of IL-6, a proinflammatory cytokine involved in neutrophil degranulation and lymphocyte differentiatio...

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Главные авторы: Sitaraman, Shanthi V., Merlin, Didier, Wang, Lixin, Wong, Michelle, Gewirtz, Andrew T., Si-Tahar, Mustapha, Madara, James L.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2001
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC199578/
https://ncbi.nlm.nih.gov/pubmed/11285305
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