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Cellular mRNA Activates Transcription Elongation by Displacing 7SK RNA

The positive transcription elongation factor P-TEFb is a pivotal regulator of gene expression in higher cells. Originally identified in Drosophila, attention was drawn to human P-TEFb by the discovery of its role as an essential cofactor for HIV-1 transcription. It is recruited to HIV transcription...

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Detalhes bibliográficos
Main Authors: Young, Tara M., Tsai, Michael, Tian, Bin, Mathews, Michael B., Pe'ery, Tsafi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1995758/
https://ncbi.nlm.nih.gov/pubmed/17925858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001010
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