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Cellular mRNA Activates Transcription Elongation by Displacing 7SK RNA
The positive transcription elongation factor P-TEFb is a pivotal regulator of gene expression in higher cells. Originally identified in Drosophila, attention was drawn to human P-TEFb by the discovery of its role as an essential cofactor for HIV-1 transcription. It is recruited to HIV transcription...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1995758/ https://ncbi.nlm.nih.gov/pubmed/17925858 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001010 |
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