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Human Mcm10 Regulates the Catalytic Subunit of DNA Polymerase-α and Prevents DNA Damage during Replication

In Saccharomyces cerevisiae, minichromosome maintenance protein (Mcm) 10 interacts with DNA polymerase (pol)-α and functions as a nuclear chaperone for the catalytic subunit, which is rapidly degraded in the absence of Mcm10. We report here that the interaction between Mcm10 and pol-α is conserved i...

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Detalhes bibliográficos
Main Authors: Chattopadhyay, Sharbani, Bielinsky, Anja-Katrin
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1995709/
https://ncbi.nlm.nih.gov/pubmed/17699597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-12-1148
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