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Rabaptin-5-independent Membrane Targeting and Rab5 Activation by Rabex-5 in the Cell
Rabex-5 is a guanine nucleotide exchange factor (GEF) for Rab5. Here, we report the identification of a novel functional domain of Rabex-5 that is essential for its membrane targeting and Rab5 GEF activity in vivo. The data show that full-length Rabex-5 efficiently activates Rab5 in the cell. Howeve...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The American Society for Cell Biology
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1995700/ https://ncbi.nlm.nih.gov/pubmed/17699593 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-02-0100 |
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