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Regulation of the desensitization and ion selectivity of ATP-gated P2X(2) channels by phosphoinositides

Phosphoinositides (PIP(n)s) are known to regulate the activity of some ion channels. Here we determined that ATP-gated P2X(2) channels also are regulated by PIP(n)s, and investigated the structural background and the unique features of this regulation. We initially used two-electrode voltage clamp t...

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Autori principali: Fujiwara, Yuichiro, Kubo, Yoshihiro
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1995631/
https://ncbi.nlm.nih.gov/pubmed/16857707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2006.115246
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