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Na(+)- and Cl(–)-coupled active transport of nitric oxide synthase inhibitors via amino acid transport system B(0,+)

Nitric oxide synthase (NOS) inhibitors have therapeutic potential in the management of numerous conditions in which NO overproduction plays a critical role. Identification of transport systems in the intestine that can mediate the uptake of NOS inhibitors is important to assess the oral bioavailabil...

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Detalhes bibliográficos
Main Authors: Hatanaka, Takahiro, Nakanishi, Takeo, Huang, Wei, Leibach, Frederick H., Prasad, Puttur D., Ganapathy, Vadivel, Ganapathy, Malliga E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC199559/
https://ncbi.nlm.nih.gov/pubmed/11306607
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