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Changes in the Free Energy Profile of Glutamate Mutase Imparted by the Mutation of an Active Site Arginine Residue to Lysine
Arginine 100 plays an important role in substrate recognition in adenosylcobalamin-dependent glutamate mutase. We have examined how the mutation of this residue to lysine affects the partitioning of tritium, incorporated at the exchangeable position of the coenzyme, between substrate and product. We...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1995565/ https://ncbi.nlm.nih.gov/pubmed/17306212 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2007.01.010 |
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