PPARα deficiency reduces insulin resistance and atherosclerosis in apoE-null mice

PPARα is a ligand-dependent transcription factor expressed at high levels in the liver. Its activation by the drug gemfibrozil reduces clinical events in humans with established atherosclerosis, but the underlying mechanisms are incompletely defined. To clarify the role of PPARα in vascular disease,...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Tordjman, Karen, Bernal-Mizrachi, Carlos, Zemany, Laura, Weng, Sherry, Feng, Chu, Zhang, Fengjuan, Leone, Teresa C., Coleman, Trey, Kelly, Daniel P., Semenkovich, Clay F.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2001
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC199556/
https://ncbi.nlm.nih.gov/pubmed/11306606
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars