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HIF-1α induced-VEGF over-expression in bone marrow stem cells protects cardiomyocytes against ischemia

Hypoxia inducible factor-1α (HIF-1α) is a proangiogenic transcription factor stabilized and activated under hypoxia. It regulates the expression of numerous target genes, including vascular endothelial growth factor (VEGF) and other cytoprotective proteins. In this study, we hypothesized that bone m...

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Detalhes bibliográficos
Main Authors: Dai, Ying, Xu, Meifeng, Wang, Yigang, Pasha, Zeeshan, Li, Tingyu, Ashraf, Muhammad
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1995444/
https://ncbi.nlm.nih.gov/pubmed/17498737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2007.04.001
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