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Crystal Structure of the Human Prostacyclin Synthase
Prostacyclin synthase (PGIS) catalyzes an isomerization of prostaglandin H(2) to prostacyclin, a potent mediator of vasodilation and anti-platelet aggregation. Here, we report the crystal structure of human PGIS at 2.15 Å resolution, which represents the first three-dimensional structure of a class...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2006
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1995163/ https://ncbi.nlm.nih.gov/pubmed/17020766 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2006.09.039 |
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