VP4 PROTEIN FROM HUMAN RHINOVIRUS 14 IS RELEASED BY PRESSURE AND LOCKED IN THE CAPSID BY THE ANTIVIRAL COMPOUND WIN

Rhinoviruses are the major causative agents of the common cold in humans. Here, we studied the stability of human rhinovirus type 14 (HRV14) under conditions of high hydrostatic pressure, low temperature, and urea in the absence and presence of an antiviral drug. Capsid dissociation and changes in t...

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Главные авторы: Gonçalves, Rafael B., Mendes, Ygara S., Soares, Marcia R., Katpally, Umesh, Smith, Thomas J., Silva, Jerson L., Oliveira, Andréa C.
Формат: Artigo
Язык:Inglês
Опубликовано: 2006
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1995025/
https://ncbi.nlm.nih.gov/pubmed/17161425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2006.11.033
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