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Exploiting noise in array CGH data to improve detection of DNA copy number change

Developing effective methods for analyzing array-CGH data to detect chromosomal aberrations is very important for the diagnosis of pathogenesis of cancer and other diseases. Current analysis methods, being largely based on smoothing and/or segmentation, are not quite capable of detecting both the ab...

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Detalhes bibliográficos
Main Authors: Hu, Jing, Gao, Jian-Bo, Cao, Yinhe, Bottinger, Erwin, Zhang, Weijia
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1994778/
https://ncbi.nlm.nih.gov/pubmed/17272296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl730
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