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Protein synthesis inhibition as a potential strategy for metabolic down-regulation
OBJECTIVE: This pilot study tested the potential of puromycin (PUR) to inhibit protein synthesis and reduce oxygen utilization in a non-hibernating, whole animal preparation. METHODS: After anesthesia and instrumentation, male rats received a single dose of PUR or 0.9% saline (control), followed 60...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2007
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1994718/ https://ncbi.nlm.nih.gov/pubmed/17250947 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.resuscitation.2006.08.029 |
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