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Crystal Structures of a Quorum-Quenching Antibody

A large number of Gram-negative bacteria employ N-acyl homoserine lactones (AHLs) as signaling molecules in quorum sensing, which is a population density-dependent mechanism to coordinate gene expression. Antibody RS2-1G9 was elicited against a lactam mimetic of the N-acyl homoserine lactone and rep...

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Bibliographic Details
Main Authors: Debler, Erik W., Kaufmann, Gunnar F., Kirchdoerfer, Robert N., Mee, Jenny M., Janda, Kim D., Wilson, Ian A.
Format: Artigo
Language:Inglês
Published: 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1994716/
https://ncbi.nlm.nih.gov/pubmed/17400249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.02.081
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